Louis-Marie Bobay
Associate Professor of Biological Sciences
Assistant Director, Bioinformatics Research Center
Ricks Hall 344
ljbobay@ncsu.edu WebsiteBio
Dr. Louis-Marie Bobay is an Associate Professor in the Department of Biological Sciences and the Bioinformatics Research Center at North Carolina State University since 2023. His background integrates genomics, microbiology, evolutionary biology, and bioinformatics. During his PhD at Pasteur institute (Paris, France), he worked on the evolution of prophages in bacteria and developed expertise in microbial evolution, population genetics and bioinformatics. As a postdoctoral fellow at UT Austin, he started working on recombination in bacteria and developed approaches that use the patterns of recombination to infer species borders in bacteria. Dr. Bobay was an Assistant Professor at the University of North Carolina Greensboro where he continued to work on these topics. He is now leading diverse projects at NCSU. He is developing new approaches to infer recombination rates in bacteria using Approximate Bayesian Computation (ABC). He is also working on diverse projects such adaptive evolution in microbes, the dynamic of gene diversity in bacteria and the processes driving population structure and speciation in microbes.
Education
M.S. Biosciences Ecole Normale Supérieure (ENS) of Lyon 2010
Ph.D. Biology Pasteur Institute 2014
Publications
- MetaStrainer : Accurate reconstruction of bacterial strain genotypes from short-read metagenomic samples , bioRxiv (Cold Spring Harbor Laboratory) (2026)
- MetaStrainer : Accurate reconstruction of bacterial strain genotypes from short-read metagenomic samples , Bioinformatics (2026)
- DEX: a consensus-based amino acid exchangeability measure for improved codon substitution modelling , bioRxiv (Cold Spring Harbor Laboratory) (2026)
- Investigating amino acid distance measures in molecular evolution models, and proposing a new consensus measure , Open MIND (2026)
- Investigating amino acid distance measures in molecular evolution models, and proposing a new consensus measure , Zenodo (CERN European Organization for Nuclear Research) (2026)
- Prevalence and Evolutionary Implications of Genome Rearrangements in Bacteria , Genome Biology and Evolution (2026)
- Co-occurrence is associated with horizontal gene transfer across marine bacteria independent of phylogeny , bioRxiv (Cold Spring Harbor Laboratory) (2025)
- Co-occurrence is associated with horizontal gene transfer across marine bacteria independent of phylogeny , The ISME Journal (2025)
- Introgression impacts the evolution of bacteria, but species borders are rarely fuzzy , Nature Communications (2025)
- MetaStrainer: Accurate reconstruction of bacterial strain genotypes from short-read metagenomic samples. , Zenodo (CERN European Organization for Nuclear Research) (2025)