Breeding Better Blueberries
Researchers Release First Chemical Map of Dyes from Historic Dye Library
The Proximity Principle

Bioinformatics is a science melting pot, bringing together many disciplines to answer big questions about our health.
Researchers Use Molecular Dynamics and Machine Learning to Create ‘Hyper-predictive’ Computer Models for Drug Discovery
Computer Simulations First Step Toward Designing New, More Efficient Amine Chemical Scrubbers
Adverse drug reactions triggered by the common HLA-B*57:01 variant: a molecular docking study
Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin.

Bioinformatics & Statistical Genetics

When the BRC at NC State University was founded in 2000, it was with the understanding that quantitative methods applied to massive datasets are essential to the comprehension of the genomic structure of even the simplest organisms.

The university is located in Raleigh, the heart of one of the leading research areas in the United States. The BRC has developed strong relationships with industrial partners and other academic or government organizations in the Research Triangle Park area.

Recent Publications

  • Linkage map construction and QTL analysis for internal heat necrosis in autotetraploid potato. A tetraploid potato population was mapped for internal heat necrosis (IHN) using the Infinium ® 8303 potato SNP array, and QTL for IHN were identified on chromosomes 1, 5, 9 and 12 that explained 28.21% of the variation for incidence and 25.3% of the variation for severity... Schumann MJ, Zeng ZB, Clough ME, Yencho GC.
  • QSAR models of human data can enrich or replace LLNA testing for human skin sensitization. Skin sensitization is a major environmental and occupational health hazard. Although many chemicals have been evaluated in humans, there have been no efforts to model these data to date... Alves VM, Capuzzi SJ, Muratov E, Braga RC, Thornton T, Fourches D, Strickland J, Kleinstreuer N, Andrade CH, Tropsha A.
  • Networks Underpinning Symbiosis Revealed Through Cross-Species eQTL Mapping. Organisms engage in extensive cross-species molecular dialogue, yet the underlying molecular actors are known for only a few interactions... Guo Y, Fudali S, Gimeno J, DiGennaro P, Chang S, Williamson VM, Bird DM, Nielsen DM.


        Jeremy Ash (Bioinformatics, Ph.D. student) recently received a fellowship for Fall 2017 from the Triangle Center of Evolutionary Medicine […]