RealityConvert: A tool for preparing 3D models of biochemical structures for augmented and virtual reality
Breeding Better Blueberries
Researchers Release First Chemical Map of Dyes from Historic Dye Library
The Proximity Principle

Bioinformatics is a science melting pot, bringing together many disciplines to answer big questions about our health.
Researchers Use Molecular Dynamics and Machine Learning to Create ‘Hyper-predictive’ Computer Models for Drug Discovery
Computer Simulations First Step Toward Designing New, More Efficient Amine Chemical Scrubbers
Adverse drug reactions triggered by the common HLA-B*57:01 variant: a molecular docking study

Bioinformatics & Statistical Genetics

When the BRC at NC State University was founded in 2000, it was with the understanding that quantitative methods applied to massive datasets are essential to the comprehension of the genomic structure of even the simplest organisms.

The university is located in Raleigh, the heart of one of the leading research areas in the United States. The BRC has developed strong relationships with industrial partners and other academic or government organizations in the Research Triangle Park area.

Recent Publications

  • Comparative dose-response analysis of liver and kidney transcriptomic effects of trichloroethylene and tetrachloroethylene in B6C3F1 mouse. Trichloroethylene (TCE) and tetrachloroethylene (PCE) are ubiquitous environmental contaminants and occupational health hazards... Zhou YH, Cichocki JA, Soldatow VY, Scholl E, Gallins P, Jima D, Yoo HS, Chiu WA, Wright FA, Rusyn I.
  • A procedure to detect general association based on concentration of ranks. In modern high-throughput applications, it is important to identify pairwise associations between variables, and desirable to use methods that are powerful and sensitive to a variety of association relationships. Rudra P, Zhou Y, Wright FA.
  • Disruption of Trim9 function abrogates macrophage motility in vivo. The vertebrate immune response comprises multiple molecular and cellular components that interface to provide defense against pathogens... Tokarz DA, Heffelfinger AK, Jima DD, Gerlach J, Shah RN, Rodriguez-Nunez I, Kortum AN, Fletcher AA, Nordone SK, Law JM, Heber S, Yoder JA.


Two students in Denis Fourches’ Cheminformatics lab recently received highly competitive ACS CINF awards at the American Chemical Society ACS […]