Tanguay & Reif labs awarded new Systems Toxicology grant!

The Environmental Protection Agency (EPA) has awarded a 3-year grant to fund a collaboration between Oregon State University (Robert Tanguay, Jane La Du, Mike Simonich, Chris Sullivan) and North Carolina State University (David Reif) entitled “System Toxicological Approaches to Define Flame Retardant Adverse Outcome Pathways”.

From the EPA webpage:

A team of researchers from Oregon State University and North Carolina State University proposes to conduct the first comprehensive in vivo,structure-activity based toxicity studies of flame retardant chemicals (FRCs), including FRCs that EPA has phased out, FRCs that companies manufacture now, and FRCs that companies have proposed as replacements. (They) will test the hypothesis that the toxicity of FRCs will be highly dependent on their chemical structure.

EPA awards grant for multi-institution collaboration between the BRC and Texas A&M

The Environmental Protection Agency (EPA) has awarded a $6 million grant to fund a multi-institutional collaboration between the Texas A&M College of Veterinary Medicine & Biomedical Sciences and the Bioinformatics Research Center at NCSU. investigating the effects of environmental toxicants on human health with a focus on the potential adverse effects on the heart. The investigators will study the effect of environmental chemicals on cultures of cells that have been coaxed into behaving like heart muscle, even to the point of beating with a regular rhythm. Dr. Fred Wright, the principal investigator for the NCSU site, says “the ability to systematically investigate cardiac toxicity in this manner opens up the study of inter-individual variability in toxicity testing, in a way that was not possible before.” Other investigators at NCSU include Associate Professor David Reif and Research Assistant Professor Yi-Hui Zhou.

Image credit: Cellular Dynamics

Link: http://today.tamu.edu/2015/06/29/epa-awards-texas-am-6-million-for-cardiac-health-related-study/